MANIFESTAÇÕES CLÍNICAS, DIAGNÓSTICO LABORATORIAL E TRATAMENTO DA PARACOCCIDIOIDOMICOSE: UMA REVISÃO NARRATIVA DA LITERATURA

CLINICAL MANIFESTATIONS, LABORATORY DIAGNOSIS AND PARACOCCIDIOIDOMYCOSIS TREATMENT: A NARRATIVE LITERATURE REVIEW

Resumen

Paracoccidioidomycosis (PCM) is a fungal infection caused by Paracoccidioides brasilensis. It is a systemic, deep and granulomatous infection that can be acquired by inhalation, by lesions on the skin or mucous membranes. It is more prevalent in males, whites, aged between 40 and 60 years old and mainly in people who work in rural activities such as agriculture and gardening. This study aimed to conduct a search in the databases on the disease, presenting clinical manifestations, laboratory diagnosis and treatment. PCM is asymptomatic, with the presence of granulomas in the tissues of affected individuals as a characteristic. It is necessary to make the differential diagnosis of some diseases such as leishmaniasis, tuberculosis, cryptococcosis, leprosy, toxoplasmosis, among other diseases that have characteristics similar to that of PCM. For diagnosis, the technique is the fresh collection of biological material such as sputum because it is low cost and highly effective. The treatment consists of evaluating the clinical form presented by the patient, however antifungals are the class of drugs of first choice for treatment. This research broadened the knowledge on the subject, enabling the viability of this little commented disease, as it still has difficulties to be diagnosed in patients, knowing that PCM is characterized by being an asymptomatic disease, alerting not only health professionals, but the general population about its existence, considering the possibility that there may be cases in individuals in smaller cities, such as Videira - SC.