Orbital - Vol. 9 No. 2 - Special Issue June 2017
FULL PAPERS

Cytotoxic and Antioxidant Activity of Mimosa verrucosa Benth.

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  • Vanessa Silva Romanoski,
  • Rauldenis Almeida Fonseca Santos
Vanessa Silva Romanoski
Universidade Federal do Oeste da Bahia
Rauldenis Almeida Fonseca Santos
Universidade Federal do Oeste da Bahia
Published May 30, 2017
Keywords
  • Mimosa verrucosa Benth,
  • jurema branca,
  • antioxidant activity,
  • Brine shrimp
How to Cite
(1)
Romanoski, V. S.; Santos, R. A. F. Cytotoxic and Antioxidant Activity of Mimosa Verrucosa Benth. Orbital: Electron. J. Chem. 2017, 9, 100-104.

Copyright (c) 2017 Orbital: The Electronic Journal of Chemistry

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Abstract

The present work describes the antioxidant and cytotoxic properties of the ethanolic extracts of the leaves and stems of Mimosa verrucosa Beth. (Fabaceae) found in Northeast Brazil. The antioxidant activity was evaluated using the stable radical sequestration essay of 2,2-diphenyl-1-picrylhydrazyl (DPPH), demonstrating that the leaves had the highest antioxidant activity (IC50= 372.7 ± 0.3 μg.mL-1) and the cytotoxic activity was obtained by evaluating the mortality of Brine shrimp larvae, revealing the highest cytotoxic potential of the roots (DL50 = 145.5 ± 21.5 μg.mL-1). The analysis of the chromatograms obtained in HPLC-DAD and the thin layer chromatography plates with specific reagents indicated the presence of steroids, flavonoids, saponins and tannins in the different extracts, to which the antioxidant and cytotoxic activities were attributed.

DOI: http://dx.doi.org/10.17807/orbital.v9i2.868

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