Orbital - Vol. 11 No. 3 - April-June 2019
FULL PAPERS

Microwave Assisted Synthesis and Antimicrobial Study of Some Novel 2-Azetidinones Derived from 2-(1-Phenylimino-ethyl)-naphthalen-1-ol

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  • Sainath Zangade,
  • Avinash Shinde,
  • Yogesh Nalwar,
  • Pravinkumar Patil
Sainath Zangade
U. G. Department of Studies in Chemistry, Madhavrao Patil ACS College, Palam
Avinash Shinde
Department of Chemistry, N.E.S. Science College, Nanded
Yogesh Nalwar
Department of Chemistry, Toshniwal ACS College, Sengaon, Dist. Hingoli
Pravinkumar Patil
Department of Chemistry, N.E.S. Science College, Nanded
Published July 6, 2019
Keywords
  • 2-azetidinones,
  • halogenohydroxy,
  • Schiff bases,
  • microwave irradiation,
  • antimicrobial activity
How to Cite
(1)
Zangade, S.; Shinde, A.; Nalwar, Y.; Patil, P. Microwave Assisted Synthesis and Antimicrobial Study of Some Novel 2-Azetidinones Derived from 2-(1-Phenylimino-Ethyl)-Naphthalen-1-Ol. Orbital: Electron. J. Chem. 2019, 11, 178-185.

Copyright (c) 2019 Orbital: The Electronic Journal of Chemistry

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Abstract

Several substituted 2‐azetidinone derivatives 2a-q have been synthesized from halogenohydroxy substituted imines 1a-q under microwave irradiation technique. The reactions were carried out using 2-methoxyethanol as an efficient reaction media to afford high yield of product. The structures of newly synthesized compounds have been established on the basis of elemental analysis, IR, 1H NMR, 13C NMR, GC-MS and elemental data. Further, all newly synthesized compounds were screened for their in vitro antimicrobial activity. The antifungal and antibacterial effects of the tested compounds are due to their molecular structure and substituent present.

DOI: http://dx.doi.org/10.17807/orbital.v11i3.1393

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