Orbital - Vol. 13 No. 3 - April-June 2021
FULL PAPERS

One-Pot Synthesis of 2,4,5-Triaryl-1H-imidazoles Using Glutamic Acid as Catalyst

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  • Bhaskar P. Ankush,
  • Balasaheb V. Shitole,
  • Nana V. Shitole
Bhaskar P. Ankush
Department of Chemistry, Kai. Rasika Mahavidyalaya
Balasaheb V. Shitole
Department of Chemistry, Vasant College Kaij
Nana V. Shitole
Shri Shivaji College S.R.T. University, Nanded
Graphical abstract
Published July 6, 2021
Keywords
  • Benzil or benzoin,
  • Glutamic acid,
  • Multicomponent reactions,
  • 2,4,5-Triaryl substituted imidazole
How to Cite
(1)
Ankush, B. P.; Shitole, B. V.; Shitole, N. V. One-Pot Synthesis of 2,4,5-Triaryl-1H-Imidazoles Using Glutamic Acid As Catalyst. Orbital: Electron. J. Chem. 2021, 13, 232-235.

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Abstract

Glutamic acid has been found to be an efficient organocatalyst for one-pot synthesis of 2,4,5-triaryl substituted imidazole by using a mixture of an aromatic aldehyde, a benzil or benzoin and an ammonium acetate in ethanol as solvent. The cleaner reaction, and easy workup make this protocol practical and economically attractive.

DOI: http://dx.doi.org/10.17807/orbital.v13i3.1611

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