Orbital - Vol. 13 No. 3 - April-June 2021
SHORT COMMUNICATIONS

A New View of a:C-H-coated Ti-6Al-4V Alloy to be Used as Orthopedic Implants: Influence of Surface Free-energy of Interaction on the Biological Responses

João Pedro Lopes Nascimento
Institute of Exact and Natural Sciences and Education, Federal University of Triângulo Mineiro (UFTM)
Leonardo dos Reis Freitas
Institute of Exact and Natural Sciences and Education, Federal University of Triângulo Mineiro (UFTM)
Camila Nunes Lemos
School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo – USP, Ribeirão Preto, São Paulo
Rogério Valentim Gelamo
Institute of Technological and Exact Sciences, Federal University of Triângulo Mineiro (UFTM)
Jéferson Aparecido Moreto
Institute of Exact and Natural Sciences and Education, Federal University of Triângulo Mineiro (UFTM)
Graphical abstract
Published July 6, 2021
Keywords
  • Biomedical application,
  • Titanium alloy,
  • Plasma treatment,
  • Functionalized surface
How to Cite
(1)
Nascimento, J. P. L.; Freitas, L. dos R.; Lemos, C. N.; Gelamo, R. V.; Moreto, J. A. A New View of a:C-H-Coated Ti-6Al-4V Alloy to Be Used As Orthopedic Implants: Influence of Surface Free-Energy of Interaction on the Biological Responses. Orbital: Electron. J. Chem. 2021, 13, 264-268.

Abstract

In a previous published work, the Ti-6Al-4V alloy were functionalized by using plasma enhanced chemical vapour deposition (PECVD) process in order to obtain hydrogenated amorphous carbon (a:C-H) on the biomaterial's surface. At the time, we noticed the functionalized surface contributed to the advance of using Ti-6Al-4V in biomedical implants applications as well as in the adding of intrinsic properties as demonstrated by electrochemical and biological assays. Here, we present new view of a-C:H-coated Ti-6Al-4V alloy, considering the influence of surface free-energy of interaction and understanding how the surface influences the biological response using pre-osteoblastic cells (MC3T3-61). Our results demonstrate, the Ti-6Al-4V containing a:C-H film has less negative value of surface free-energy when compared to the bare material (-22.156 mJ m-2 vs. -60.046 mJ m-2), suggesting a tendency toward to a less hydrophobic surface which is extremely important to reduce the inflammatory process, common in orthopedic implants.

DOI: http://dx.doi.org/10.17807/orbital.v13i3.1622