REVIEWS
Published
October 5, 2021
Keywords
- gamma-butyrolactone,
- maculalactone,
- microwave-assisted synthesis,
- multicomponent reaction,
- MCR
- one-pot reaction ...More
How to Cite
(1)
Donate, P. M.; Barbosa, H. E. Microwave Radiation Applied to the Synthesis of -Butyrolactone Derivatives. Orbital: Electron. J. Chem. 2021, 13, 376-384.
Copyright (c) 2021 Orbital: The Electronic Journal of Chemistry
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Abstract
Many natural products with a broad spectrum of biological effects bear the g-butyrolactone ring. Given the difficulty in isolating large amounts of butyrolactones from natural sources, interest in synthesizing structural analogs of these compounds and in studying their biological properties has increased. In this review, we summarize the main synthetic methodologies to construct γ-butyrolactone derivatives by using multicomponent processes.